Wanze CHENProfessor

The research focus of Dr. Chen's lab is to understand and further program the fate of stem cells. Driven by this primary interest, they actively develop and utilize multidisciplinary technologies to address the methodologically inaccessible questions.

Wanze Chen is a professor at Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences. Dr. Chen received his Ph.D. from Xiamen University, China. He then studied in the Laboratory of Systems Biology and Genetics as a postdoc in EPFL in Switzerland before joining the faculty at SIAT.  

Email: wz.chen@siat.ac.cn

Publications/Patents (selected)

Chen, W. #, Guillaume-Gentil, O. #, Dainese, R., Rainer, P., Zachara, M., Gäbelein, C., Vorholt, J., Deplancke, B. Live cell transcriptome profiling using Live-seq. (bioRxiv, 2021)

Chen W#, Schwalie PC#, et al., ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer. Nature Communications (2019)

Chen W, Gardeux V, et al., Profiling of Single-Cell Transcriptomes. Current Protocols in Mouse Biology (2017)

Chen W, Wu J, et al., Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nature Cell Biology (2015)

Li L#, Chen W#, Liang Y#, et al., Gβγ-Src signaling pathway via control of the translocation of necrosome regulates TNF-induced necroptosis. Cell Research (2014)

Chen W#, Zhou Z#, Li L#, et al., Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling. J Biol Chem (2013)