Prof. Lixin Zhang is Director of State Key Laboratory of Bioreactor Engineering, School of Biotechnology, East China University of Science and Technology. He is also Part-time Professor of Institute of Microbiology, Chinese Academy of Sciences (IMCAS). He is Chief Scientist of a “973 Program” and an Awardee of the National Science Fund for Distinguished Young Scholars, China. He received his Ph. D degree in Institute of Applied Ecology, CAS and did his postdoc at Emory University, USA. He has published seven books, more than 200 papers and holds 28 Chinese patents and 16 PCT patents. He served as the President of the International Chemical Biology Society (ICBS) during 2016-8. He became the president of SLAS Asia Regional Board, Society for Laboratory Automation and Screening in early 2015. He was recognized as an Honorary lifetime member, Sino-American Pharmaceutical Professional Association (SAPA). He has been appointed as an Editor-in-Chief for "Synthetic and Systems Biotechnology", Associate Editor-in-Chief for Applied Microbiology and Biotechnology. He also served as an Executive Board Member of International Committee on the Biology of Actinomycetes (ISBA) and the GIM (Genetics of Industrial Microorganisms).
Email:lxzhang@ecust.edu.cn
Website:http://biotech.ecust.edu.cn/2016/1019/c7935a56621/page.htm/ http://zhanglab.caspmi.cn
Publications/Patents(recent)
Weishan Wang, Shanshan Li, Zilong Li, Jingyu Zhang, Keqiang Fan, Gaoyi Tan, Guomin Ai, Sin Man Lam, Guanghou Shui, Zhiheng Yang, Hongzhong Lu, Pinjiao Jin, Yihong Li, Xiangyin Chen, Xuekui Xia, Xueting Liu, H. Kathleen Dannelly, Chen Yang, Yi Yang, Siliang Zhang, Gil Alterovitz, Wensheng Xiang*, Lixin Zhang*. 2019. Harnessing cellular triacylglycerol pool for titer improvement of polyketides in Streptomyces. Nat. Biotechnol. IF= 35.724
Mindong Liang, Zilong Li, Weishan Wang, Jiakun Liu, Leshi Liu, Guoliang Zhu, Loganathan Karthik, Man Wang, Ke-Feng Wang, Zhong Wang, Jing Yu, Yuting Shuai, Jiaming Yu, Lu Zhang, Zhiheng Yang, Chuan Li, Qian Zhang, Tong Shi, Liming Zhou, Feng Xie, Huanqin Dai, Xueting Liu, Jingyu Zhang, Guang Liu, Ying Zhuo, Buchang Zhang, Chenli Liu, Shanshan Li, Xuekui Xia, Yaojun Tong, Yanwen Liu, Gil Alterovitz, Gao-Yi Tan * & Li-Xin Zhang *. 2019. A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules. Nature communications. 2019 Aug 14;10(1):3672. doi: 10.1038/s41467-019-11648-1 IF=12.124
Cao, J.#, Yao, Y.#, Fan, K., Tan, G., Xiang, W., Xia, X., Li, S.*, Wang, W.*, and Zhang L*. 2018. Harnessing a novel capability of bacterial allosteric transcription factors for sensing diverse small molecules in vitro. Sci Adv, (doi: 10.1126/sciadv.aau4602) IF=11.51
1.Wupeng Yan, Heng Song, Fuhang Song, Yisong Guo, Cheng-Hsuan Wu, Ampon Sae Her, Yi Pu, Shu Wang, Nathchar Naowarojna, Andrew Weitz, Michael P. Hendrich, Catherine E. Costello, Zhang Lixin*, Pinghua Liu*, and Yan Jessie Zhang*. 2015. Endoperoxide Formation Catalyzed by FtmOx1, an α-Ketoglutarate-dependent Mononuclear Non-heme Iron Enzyme. Nature, 527, 539–543. (IF＝41.296)
2.Wang Minxuan, Carver Jeremy J, Shi Wenyuan, Liu Xueting, Zhang Lixin, Knight Rob, Moore Bradley S, Dorrestein Pieter C*, Bandeira Nuno*, et al. 2016. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34(8):828-837. doi: 10.1038/nbt.3597. (IF=43.113)
3.Wang Qian, Song Fuhang, Xiao Xue, Huang Pei, Li Li, Aaron Monte, Wael M. Abdel-Mageed, Wang Jian, Guo Hui, He Wenni, Xie Feng, Dai Huanqin, Liu Miaomiao, Chen Caixia, Xu Hao, Liu Mei, Andrew M. Piggott, Liu Xueting*, Robert J. Capon*, Zhang Lixin*. Abyssomicins from the South China Sea deep-sea sediment Verrucosispora sp.: Natural thioether Michael addition adducts as antitubercular prodrugs. Angew. Chem.-Int. Edit. 2013,52, 1231-1234. (IF＝13.560)
4.Bai C, Zhang Y, Zhao X, Hu Y, Xiang S, Miao J, Lou C*, Zhang L*. 2015. Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces. Proc Natl Acad Sci U S A. 112 (39), 12181-6. (IF＝10.6)
5.Ashforth Elizabeth Jane, Fu Chengzhang, Liu Xiangyang, Dai Huanqin, Song Fuhang, Guo Hui, Zhang Lixin*. Bioprospecting for antituberculosis leads from microbial metabolites. Nat Prod Rep.2010,27, 1709-1719. (IF＝9.8)
monograph
Zhang, L.*, and A. Demain*. (Editors-in-Chief) 2005. “Natural Products: Drug Discovery, Therapeutic Medicine”, ISBN: 1-58829-383-1, Humana Press, USA. (30,570downloads)
Lin, J; Nishino, K; Roberts, MC; Tolmasky, M; Aminov, RI; Zhang, L.* 2015. Mechanisms of antibiotic resistance, DOI: 10.3389/fmicb.2015.00034 (eBook) (37,468 downloads)