Junbiao DAIDistinguished Visting Professor

The research interest lie in synthetic biology using different model organisms, focusing on development of new technologies for genes synthesis, assembly and synthetic genomics.

Professor Junbiao Dai received his Bachelor degree from Nanjing University in 1997, Master of Science in Biology from Tsinghua University in 2000 and PhD in Molecular, Cellular and Developmental Biology from Iowa State University in 2006. He was a post-doctoral fellow at the Johns Hopkins University School of Medicine before joining the faculty in School of Life Sciences at Tsinghua University in 2011. In 2017, he joined the faculty at SIAT.

Dr. Dai's research interests lie in synthetic biology using different model organisms, focusing on development of new technologies for genes synthesis, assembly and synthetic genomics. In the past five years, he has published, as corresponding author, more than 40 papers in prestigious journals including Science and was selected as one of the Top Ten Scientific Advances of China in 2017. He is one of the key members in synthetic yeast consortium (Sc2.0) and genome project-write (GP-write), and is currently leading the "GP-Write China". In 2017, He was awarded the National Science Fund for Distinguished Young Scholars.

TEL:0755-86525464

EMAIL:junbiao.dai@siat.ac.cn

WEBSITE:http://isynbio.siat.ac.cn/dailab/


Publications/Patents (selected)

Zhang W#, Zhang X#, Xue Z#, Li Y#, Ma Q, Ren X, Zhang J, Yang S, Yang L, Wu M, Ren M, Xi R, Wu Z, Liu J, Matunis E, Dai J*, Gao G*, Probing the function of metazoan histones with a systematic library of H3 and H4 mutants, Developmental Cell, 2019, 48: 1-14. 

Liu W, Luo Z, Wang Y, Pham N, Tuck L, Pi I, Liu L, Shen Y, French C, Auer M, Wright J, Dai J*, Cai Y*, Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods, Nature communications, 2018, 9: 1936.

[Luo Z#, Wang L#, Wang Y, Zhang W, Guo Y, Shen Y, Jiang L, Wu Q, Zhang C, Cai Y*, Dai J*, Identifing and characterizing SCRaMbLEd synthetic yeast using ReSCuES, Nature communications, 2018, 8, 9: 1930.

Huang J#, Luo Z#, Ying W#, Cao Q, Huang H, Dong J, Wu Q, Zhao Y, Qian X*, Dai J*, 2-hydroxyisobutyrylation on histone H4K8 is regulated by glucose homeostasis in Saccharomyces cerevisiae. PNAS, 2017, 114(33): 8782-8787. 

Zhang W#, Zhao G#, Luo Z#, Lin Y, Wang L, Guo Y, Wang A, Jiang S, Jiang Q, Gong J, Wang Y, Hou S, Huang J, Li T, Qin Y, Dong J,Qin Q, Zhang J, Zou X, He X, Zhao L, Xiao Y, Xu M, Cheng E, Huang N, Zhou T, Shen Y, Walker R, Luo Y, Kuang Z, Mitchell LA, Yang K, Richardson SM, Wu Y, Li B, Yuan Y, Yang H, Lin J, Chen G, Wu Q, Bader JS, Cai Y, Boeke JD, Dai J*, Engineering the ribosomal DNA in a megabase synthetic chromosome, Science, 2017, 355(6329).