Dr. Landian Hu is a principal investigator of Shanghai Institutes for Biological Sciences, CAS. After graduating from NANKAI University, Dr. Hu has been one of the visiting scholars at Max Planck Institute for Molecular Genetics(Germany) and MRC Laboratory of Molecular Biology(UK). Dr. Hu is majoring in the research on genetic research of human diseases related and tumor immunotherapy. As the principal investigator, she has led and taken part in many import scientific projects, including projects of National Science Foundation of China, National 973 project, and so on. Besides, Dr Hu is also one of the review experts of National Science Foundation of China. During her research, Dr. Hu has published about 50 SCI papers and also won the first prize of Shanghai science and technology progress award.
EMAIL: ldhu@sibs.ac.cn
Publications/Patents (recent)
Yin S, Deng W, Hu L, Kong X.The impact of nucleosome positioning on the organization of replication origins in eukaryotes. Biochem Biophys Res Commun. 2009 Jul 31;385(3):363-8.
Zhang Z, Xin D, Wang P, Zhou L, Hu L, Kong X, Hurst LD. Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay. BMC Biol. 2009 May 14;7:23.
Wang ZQ, Si L, Tang Q, Lin D, Fu Z, Zhang J, Cui B, Zhu Y, Kong X, Deng M, Xia Y, Xu H, Le W, Hu L, Kong X.Gain-of-function mutation of KIT ligand on melanin synthesis causes familial progressive hyperpigmentation. Am J Hum Genet. 2009 May;84(5):672-7.
Yin S, Deng W, Zheng H, Zhang Z, Hu L, Kong X. Evidence that the nonsense-mediated mRNA decay pathway participates in X chromosome dosage compensation in mammals. Biochem Biophys Res Commun. 2009 Jun 5;383(3):378-82.
Shi X, Cui B, Wang Z, Weng L, Xu Z, Ma J, Xu G, Kong X, Hu L. Removal of Hsf4 leads to cataract development in mice through down-regulation of gamma S-crystallin and Bfsp expression. BMC Mol Biol. 2009 Feb 19;10:10.
Wang P, Yin S, Zhang Z, Xin D, Hu L, Kong X, Hurst LD. Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes. Genome Biol. 2008 Dec 2;9(12):R169.