Hanjie LIProfessor

Tumor Immunology, Synthetic Immunology, Single cell genomics, T cell biology

Dr. Hanjie Li obtained his PhD from Xiamen University in 2014 under the supervision of Dr. Jiahuai Han. From 2016 to 2020, he was a post-doc fellow in the Department of Immunology in Weizmann Institute of Science. During his post-doc, Dr. Li developed and applied state-of-the-art single cell technology to dissect the interaction between tumor and the immune system. He is the recipients of many prestigious awards, including Humboldt Fellowship and Marie Curie Fellowship. Dr. Li has published in many top journals including, Cell, Cell Research, Cell Reports, Cellular & Molecular Immunology, Journal of Immunology, etc.

The Li Lab will continue to integrate single cell genomics, computational biology, cellular and molecular biology to unveil the role of the immune system in health and disease. Meanwhile, the lab is also dedicated to rationally design and engineer immune cells, molecules, and pathways for the purpose of immune-based diagnosis and therapeutics. 

EMAIL: hj.li@siat.ac.cn

Publications/Patents (recent)

Hanjie Li#, Anne M van der Leun#, Ido Yofe#, Yaniv Lubling#, Dikla Gelbard-Solodkin, Alexander C J van Akkooi, Marlous van den Braber, Elisa A Rozeman, John B A G Haanen, Christian U Blank, Hugo M Horlings, Eyal David, Yael Baran, Akhiad Bercovich, Aviezer Lifshitz, Ton N Schumacher*, Amos Tanay*, Ido Amit*, Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment Within Human Melanoma, Cell, 2019, 176(4): 775-789

Hanjie Li, Congting Ye, Guoli Ji, Jiahuai Han, Determinants of Public T Cell Responses, Cell Research, 2012, 22(1): 33-42

Hanjie Li#, Qiuyu Zhuang#, Yuze Wang#, Tianying Zhang, Jinghua Zhao, Yali Zhang, Junfang Zhang, Yi Lin, Quan Yuan, Ningshao Xia*, Jiahuai Han*, HBV Life Cycle Is Restricted in Mouse Hepatocytes Expressing Human NTCP, Cellular & Molecular Immunology, 2014, 11(2): 175-83

Hanjie Li#, Congting Ye#, Guoli Ji, Xiaohui Wu, Zhe Xiang, Yuanyue Li, Yonghao Cao, Xiaolong Liu, Daniel C Douek, David A Price*, Jiahuai Han*, Recombinatorial Biases and Convergent Recombination Determine Interindividual TCRβ Sharing in Murine Thymocytes, Journal of Immunology, 2012, 189(5): 2404-13

Juan Lin#, Hanjie Li#, Min Yang, Junming Ren, Zhe Huang, Felicia Han, Jian Huang, Jianhui Ma, Duanwu Zhang, Zhirong Zhang, Jianfeng Wu, Deli Huang, Muzhen Qiao, Guanghui Jin, Qiao Wu, Yinghui Huang, Jie Du*, Jiahuai Han*, A Role of RIP3-mediated Macrophage Necrosis in Atherosclerosis Development, Cell Reports, 2013, 3(1): 200-210